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Research Article

Accurate Quantification of Functional Analogy among Close Homologs

  • Maria D. Chikina,

    Affiliation: Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Olga G. Troyanskaya mail

    ogt@cs.princeton.edu

    Affiliations: Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America, Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America

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  • Published: February 03, 2011
  • DOI: 10.1371/journal.pcbi.1001074

About the Authors

Maria D. Chikina
Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
Olga G. Troyanskaya
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America
Olga G. Troyanskaya
Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America

Corresponding Author

Email: ogt@cs.princeton.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDC OGT. Performed the experiments: MDC. Analyzed the data: MDC. Wrote the paper: MDC OGT.