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Research Article

Emergence of Switch-Like Behavior in a Large Family of Simple Biochemical Networks

  • Dan Siegal-Gaskins mail,

    dsg@mbi.osu.edu

    Affiliations: Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America, Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, Ohio, United States of America

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  • Maria Katherine Mejia-Guerra,

    Affiliation: Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, Ohio, United States of America

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  • Gregory D. Smith,

    Affiliation: Department of Applied Science, The College of William and Mary, Williamsburg, Virginia, United States of America

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  • Erich Grotewold

    Affiliation: Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, Ohio, United States of America

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  • Published: May 12, 2011
  • DOI: 10.1371/journal.pcbi.1002039

About the Authors

Dan Siegal-Gaskins
Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America
Dan Siegal-Gaskins, Maria Katherine Mejia-Guerra, Erich Grotewold
Department of Molecular Genetics and Plant Biotechnology Center, The Ohio State University, Columbus, Ohio, United States of America
Gregory D. Smith
Department of Applied Science, The College of William and Mary, Williamsburg, Virginia, United States of America

Corresponding Author

Email: dsg@mbi.osu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DSG GDS EG. Performed the experiments: DSG MKMG GDS. Analyzed the data: DSG MKMG. Contributed reagents/materials/analysis tools: DSG GDS. Wrote the paper: DSG MKMG GDS EG.