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Research Article

Optimal Stimulus Shapes for Neuronal Excitation

  • Daniel B. Forger mail,

    forger@umich.edu

    Affiliations: Department of Mathematics and Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America, Marine Biological Laboratory, Woods Hole, Massachusetts, United States of America

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  • David Paydarfar,

    Affiliations: Marine Biological Laboratory, Woods Hole, Massachusetts, United States of America, Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, United States of America, Departments of Neurology and Physiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • John R. Clay

    Affiliations: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America, Marine Biological Laboratory, Woods Hole, Massachusetts, United States of America

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  • Published: July 07, 2011
  • DOI: 10.1371/journal.pcbi.1002089

About the Authors

Daniel B. Forger
Department of Mathematics and Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America
Daniel B. Forger, David Paydarfar, John R. Clay
Marine Biological Laboratory, Woods Hole, Massachusetts, United States of America
David Paydarfar
Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, Massachusetts, United States of America
David Paydarfar
Departments of Neurology and Physiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
John R. Clay
National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: forger@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DBF DP. Performed the experiments: JRC. Analyzed the data: DBF. Wrote the paper: DBF DP JRC.