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Research Article

Cadherin-Dependent Cell Morphology in an Epithelium: Constructing a Quantitative Dynamical Model

  • Ian M. Gemp,

    Affiliation: Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois, United States of America

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  • Richard W. Carthew,

    Affiliation: Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America

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  • Sascha Hilgenfeldt mail

    sascha@illinois.edu

    Affiliation: Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

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  • Published: July 21, 2011
  • DOI: 10.1371/journal.pcbi.1002115

About the Authors

Ian M. Gemp
Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois, United States of America
Richard W. Carthew
Department of Molecular Biosciences, Northwestern University, Evanston, Illinois, United States of America
Sascha Hilgenfeldt
Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

Corresponding Author

Email: sascha@illinois.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RWC. Analyzed the data: IMG SH. Contributed reagents/materials/analysis tools: SH. Wrote the paper: IMG SH. Performed Numerical Simulations: IMG. Developed theory: IMG SH.