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Research Article

Genome-Scale Analysis of Translation Elongation with a Ribosome Flow Model

  • Shlomi Reuveni equal contributor,

    equal contributor Contributed equally to this work with: Shlomi Reuveni, Tamir Tuller

    Affiliations: Department of Statistics and Operations Research, School of Mathematical Sciences, Tel Aviv University, Ramat Aviv, Israel, School of Chemistry, Tel Aviv University, Ramat Aviv, Israel

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  • Isaac Meilijson,

    Affiliation: Department of Statistics and Operations Research, School of Mathematical Sciences, Tel Aviv University, Ramat Aviv, Israel

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  • Martin Kupiec,

    Affiliation: Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv, Israel

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  • Eytan Ruppin,

    Affiliations: School of Computer Sciences, Tel Aviv University, Ramat Aviv, Israel, School of Medicine, Tel Aviv University, Ramat Aviv, Israel

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  • Tamir Tuller equal contributor mail

    equal contributor Contributed equally to this work with: Shlomi Reuveni, Tamir Tuller

    tamir.tuller@weizmann.ac.il

    Affiliations: Faculty of Mathematics and Computer Science, Weizmann Institute of Science, Rehovot, Israel, Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

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  • Published: September 01, 2011
  • DOI: 10.1371/journal.pcbi.1002127

About the Authors

Shlomi Reuveni, Isaac Meilijson
Department of Statistics and Operations Research, School of Mathematical Sciences, Tel Aviv University, Ramat Aviv, Israel
Shlomi Reuveni
School of Chemistry, Tel Aviv University, Ramat Aviv, Israel
Martin Kupiec
Molecular Microbiology and Biotechnology, Tel Aviv University, Ramat Aviv, Israel
Eytan Ruppin
School of Computer Sciences, Tel Aviv University, Ramat Aviv, Israel
Eytan Ruppin
School of Medicine, Tel Aviv University, Ramat Aviv, Israel
Tamir Tuller
Faculty of Mathematics and Computer Science, Weizmann Institute of Science, Rehovot, Israel
Tamir Tuller
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel

Corresponding Author

Email: tamir.tuller@weizmann.ac.il

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SR TT. Performed the experiments: SR TT. Analyzed the data: SR TT. Wrote the paper: SR IM MK ER TT.