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Research Article

Conflicting Biomedical Assumptions for Mathematical Modeling: The Case of Cancer Metastasis

  • Anna Divoli,

    Affiliations: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America, Institute for Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America

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  • Eneida A. Mendonça,

    Affiliations: Department of Pediatrics, University of Chicago, Chicago, Illinois, United States of America, Computation Institute, University of Chicago, Chicago, Illinois, United States of America

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  • James A. Evans,

    Affiliations: Computation Institute, University of Chicago, Chicago, Illinois, United States of America, Department of Sociology, University of Chicago, Chicago, Illinois, United States of America

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  • Andrey Rzhetsky mail

    arzhetsky@uchicago.edu

    Affiliations: Department of Medicine, University of Chicago, Chicago, Illinois, United States of America, Institute for Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America, Computation Institute, University of Chicago, Chicago, Illinois, United States of America, Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

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  • Published: October 06, 2011
  • DOI: 10.1371/journal.pcbi.1002132

About the Authors

Anna Divoli, Andrey Rzhetsky
Department of Medicine, University of Chicago, Chicago, Illinois, United States of America
Anna Divoli, Andrey Rzhetsky
Institute for Genomics and Systems Biology, University of Chicago, Chicago, Illinois, United States of America
Eneida A. Mendonça
Department of Pediatrics, University of Chicago, Chicago, Illinois, United States of America
Eneida A. Mendonça, James A. Evans, Andrey Rzhetsky
Computation Institute, University of Chicago, Chicago, Illinois, United States of America
James A. Evans
Department of Sociology, University of Chicago, Chicago, Illinois, United States of America
Andrey Rzhetsky
Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

Corresponding Author

Email: arzhetsky@uchicago.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AD JAE AR. Performed the experiments: AD EAM JAE AR. Analyzed the data: AD JAE AR. Wrote the paper: AD JAE AR.