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Research Article

Change in Allosteric Network Affects Binding Affinities of PDZ Domains: Analysis through Perturbation Response Scanning

  • Z. Nevin Gerek,

    Affiliations: Center for Biological Physics, Arizona State University, Tempe, Arizona, United States of America, Department of Physics, Arizona State University, Tempe, Arizona, United States of America

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  • S. Banu Ozkan mail

    Banu.Ozkan@asu.edu

    Affiliations: Center for Biological Physics, Arizona State University, Tempe, Arizona, United States of America, Department of Physics, Arizona State University, Tempe, Arizona, United States of America

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  • Published: October 06, 2011
  • DOI: 10.1371/journal.pcbi.1002154

About the Authors

Z. Nevin Gerek, S. Banu Ozkan
Center for Biological Physics, Arizona State University, Tempe, Arizona, United States of America
Z. Nevin Gerek, S. Banu Ozkan
Department of Physics, Arizona State University, Tempe, Arizona, United States of America

Corresponding Author

Email: Banu.Ozkan@asu.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZNG SBO. Performed the experiments: ZNG SBO. Analyzed the data: ZNG SBO. Contributed reagents/materials/analysis tools: ZNG SBO. Wrote the paper: ZNG SBO.