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Research Article

Using Structure to Explore the Sequence Alignment Space of Remote Homologs

  • Andrew Kuziemko,

    Affiliations: Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

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  • Barry Honig,

    Affiliations: Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

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  • Donald Petrey mail

    dsp18@columbia.edu

    Affiliations: Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

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  • Published: October 06, 2011
  • DOI: 10.1371/journal.pcbi.1002175

About the Authors

Andrew Kuziemko, Barry Honig, Donald Petrey
Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, United States of America
Andrew Kuziemko, Barry Honig, Donald Petrey
Center for Computational Biology and Bioinformatics, Columbia University, New York, New York, United States of America

Corresponding Author

Email: dsp18@columbia.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AK BH DP. Performed the experiments: AK. Analyzed the data: AK BH DP. Contributed reagents/materials/analysis tools: AK DP. Wrote the paper: AK BH DP.