Decoding Complex Chemical Mixtures with a Physical Model of a Sensor Array

Julia Tsitron; Addison D. Ault; James R. Broach; Alexandre V. Morozov

doi:10.1371/journal.pcbi.1002224

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Open Access

Peer-reviewed

Research Article

Decoding Complex Chemical Mixtures with a Physical Model of a Sensor Array

Julia Tsitron ,

Contributed equally to this work with: Julia Tsitron, Addison D. Ault

Affiliation Department of Physics & Astronomy and BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America
⨯
Addison D. Ault ,

Contributed equally to this work with: Julia Tsitron, Addison D. Ault

Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
⨯
James R. Broach,

Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America
⨯
Alexandre V. Morozov

* E-mail: morozov@physics.rutgers.edu

Affiliation Department of Physics & Astronomy and BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America
⨯

Decoding Complex Chemical Mixtures with a Physical Model of a Sensor Array

Julia Tsitron,
Addison D. Ault,
James R. Broach,
Alexandre V. Morozov

Published: October 20, 2011
https://doi.org/10.1371/journal.pcbi.1002224

About the Authors

Julia Tsitron

Contributed equally to this work with: Julia Tsitron, Addison D. Ault

Affiliation Department of Physics & Astronomy and BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America

Addison D. Ault

Contributed equally to this work with: Julia Tsitron, Addison D. Ault

Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

James R. Broach

Affiliation Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

Alexandre V. Morozov

* E-mail: morozov@physics.rutgers.edu

Affiliation Department of Physics & Astronomy and BioMaPS Institute for Quantitative Biology, Rutgers University, Piscataway, New Jersey, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ADA JRB. Performed the experiments: ADA. Analyzed the data: JT AVM. Wrote the paper: ADA AVM.

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Receptor-ligand binding assay
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Olfactory receptor neurons
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Free energy
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Olfactory system
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Pattern recognition receptors
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Sensory perception
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G protein coupled receptors
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Odorants
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