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Research Article

Speed, Sensitivity, and Bistability in Auto-activating Signaling Circuits

  • Rutger Hermsen mail,

    hermsen@ctbp.ucsd.edu

    Affiliation: Center for Theoretical Biological Physics and Department of Physics, University of California at San Diego, La Jolla, California, United States of America

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  • David W. Erickson,

    Affiliation: Center for Theoretical Biological Physics and Department of Physics, University of California at San Diego, La Jolla, California, United States of America

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  • Terence Hwa

    Affiliation: Center for Theoretical Biological Physics and Department of Physics, University of California at San Diego, La Jolla, California, United States of America

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  • Published: November 17, 2011
  • DOI: 10.1371/journal.pcbi.1002265

About the Authors

Rutger Hermsen, David W. Erickson, Terence Hwa
Center for Theoretical Biological Physics and Department of Physics, University of California at San Diego, La Jolla, California, United States of America

Corresponding Author

Email: hermsen@ctbp.ucsd.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RH DWE TH. Performed the experiments: RH DWE. Analyzed the data: RH DWE TH. Wrote the paper: RH.