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Research Article

Multiscale Modeling of Red Blood Cell Mechanics and Blood Flow in Malaria

  • Dmitry A. Fedosov,

    Affiliations: Division of Applied Mathematics, Brown University, Providence, Rhode Island, United States of America, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, Jülich, Germany

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  • Huan Lei,

    Affiliation: Division of Applied Mathematics, Brown University, Providence, Rhode Island, United States of America

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  • Bruce Caswell,

    Affiliation: School of Engineering, Brown University, Providence, Rhode Island, United States of America

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  • Subra Suresh,

    Affiliation: Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • George E. Karniadakis mail

    george_karniadakis@brown.edu

    Affiliation: Division of Applied Mathematics, Brown University, Providence, Rhode Island, United States of America

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  • Published: December 01, 2011
  • DOI: 10.1371/journal.pcbi.1002270

About the Authors

Dmitry A. Fedosov, Huan Lei, George E. Karniadakis
Division of Applied Mathematics, Brown University, Providence, Rhode Island, United States of America
Dmitry A. Fedosov
Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, Jülich, Germany
Bruce Caswell
School of Engineering, Brown University, Providence, Rhode Island, United States of America
Subra Suresh
Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: george_karniadakis@brown.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BC SS GEK. Performed the experiments: DAF HL. Analyzed the data: DAF HL BC SS GEK. Contributed reagents/materials/analysis tools: DAF HL. Wrote the paper: DAF HL BC SS GEK. Performed research, analyzed results and wrote part of the paper: DAF HL. Designed the research, analyzed the results and wrote parts of the paper: BC SS GEK.