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Research Article

Dynamics of Mutant Cells in Hierarchical Organized Tissues

  • Benjamin Werner mail,

    werner@evolbio.mpg.de (BW); traulsen@evolbio.mpg.de (AT)

    Affiliation: Evolutionary Theory Group, Max-Planck-Institute for Evolutionary Biology, Plön, Germany

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  • David Dingli,

    Affiliation: Division of Hematology, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America

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  • Tom Lenaerts,

    Affiliations: MLG, Département d'Informatique, Université Libre de Bruxelles, Brussels, Belgium, AI-LAB Computer Science Department, Vrije Universiteit Brussel, Brussels, Belgium

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  • Jorge M. Pacheco,

    Affiliations: Departmento de Matemática e Aplicacões, Universidade do Minho, Braga, Portugal, ATP-group, CMAF, Lisboa, Portugal

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  • Arne Traulsen mail

    werner@evolbio.mpg.de (BW); traulsen@evolbio.mpg.de (AT)

    Affiliation: Evolutionary Theory Group, Max-Planck-Institute for Evolutionary Biology, Plön, Germany

    X
  • Published: December 01, 2011
  • DOI: 10.1371/journal.pcbi.1002290

About the Authors

Benjamin Werner, Arne Traulsen
Evolutionary Theory Group, Max-Planck-Institute for Evolutionary Biology, Plön, Germany
David Dingli
Division of Hematology, Mayo Clinic, College of Medicine, Rochester, Minnesota, United States of America
Tom Lenaerts
MLG, Département d'Informatique, Université Libre de Bruxelles, Brussels, Belgium
Tom Lenaerts
AI-LAB Computer Science Department, Vrije Universiteit Brussel, Brussels, Belgium
Jorge M. Pacheco
Departmento de Matemática e Aplicacões, Universidade do Minho, Braga, Portugal
Jorge M. Pacheco
ATP-group, CMAF, Lisboa, Portugal

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BW DD TL JMB AT. Performed the experiments: BW AT. Wrote the paper: BW DD TL JMB AT.