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Research Article

Predictability of Evolutionary Trajectories in Fitness Landscapes

  • Alexander E. Lobkovsky,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Yuri I. Wolf,

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Eugene V. Koonin mail

    koonin@ncbi.nlm.nih.gov

    Affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: December 15, 2011
  • DOI: 10.1371/journal.pcbi.1002302

About the Authors

Alexander E. Lobkovsky, Yuri I. Wolf, Eugene V. Koonin
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: koonin@ncbi.nlm.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AEL YIW EVK. Performed the experiments: AEL. Analyzed the data: AEL YIW EVK. Contributed reagents/materials/analysis tools: AEL. Wrote the paper: AEL EVK.