Advertisement
Research Article

Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes

  • Amin R. Mazloom,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Ruth Dannenfelser,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Neil R. Clark,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Arsen V. Grigoryan,

    Affiliation: Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

    X
  • Kathryn M. Linder,

    Affiliation: Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

    X
  • Timothy J. Cardozo,

    Affiliation: Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

    X
  • Julia C. Bond,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Aislyn D. W. Boran,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Ravi Iyengar,

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Anna Malovannaya,

    Affiliation: Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Rainer B. Lanz,

    Affiliation: Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

    X
  • Avi Ma'ayan mail

    avi.maayan@mssm.edu

    Affiliation: Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

    X
  • Published: December 29, 2011
  • DOI: 10.1371/journal.pcbi.1002319

About the Authors

Amin R. Mazloom, Ruth Dannenfelser, Neil R. Clark, Julia C. Bond, Aislyn D. W. Boran, Ravi Iyengar, Avi Ma'ayan
Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America
Arsen V. Grigoryan, Kathryn M. Linder, Timothy J. Cardozo
Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America
Anna Malovannaya, Rainer B. Lanz
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Corresponding Author

Email: avi.maayan@mssm.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: A. Ma'ayan, A. Mazloom, A. Boran, A. Grigoryan. Performed the experiments: A. Ma'ayan, A. Mazloom, A. Malovannaya, R. Dannenfelser, J. Bond, K. Linder, A. Boran, A. Grigoryan. Analyzed the data: A. Ma'ayan, A. Mazloom, A. Malovannaya, N. Clark, A. Boran, A. Grigoryan. Contributed reagents/materials/analysis tools: A. Malovannaya, R. Lanz, T. Cardozo, R. Iyengar. Wrote the paper: A. Ma'ayan, A. Mazloom, A. Malovannaya, R. Lanz, N. Clark.