About the Authors

Amin R. Mazloom

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Ruth Dannenfelser

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Neil R. Clark

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Arsen V. Grigoryan

Affiliation Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

Kathryn M. Linder

Affiliation Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

Timothy J. Cardozo

Affiliation Department of Pharmacology, New York University School of Medicine, New York, New York, United States of America

Julia C. Bond

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Aislyn D. W. Boran

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Ravi Iyengar

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Anna Malovannaya

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Rainer B. Lanz

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Avi Ma'ayan

avi.maayan@mssm.edu

Affiliation Department of Pharmacology and Systems Therapeutics, Systems Biology Center New York (SBCNY), Mount Sinai School of Medicine, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: A. Ma'ayan, A. Mazloom, A. Boran, A. Grigoryan. Performed the experiments: A. Ma'ayan, A. Mazloom, A. Malovannaya, R. Dannenfelser, J. Bond, K. Linder, A. Boran, A. Grigoryan. Analyzed the data: A. Ma'ayan, A. Mazloom, A. Malovannaya, N. Clark, A. Boran, A. Grigoryan. Contributed reagents/materials/analysis tools: A. Malovannaya, R. Lanz, T. Cardozo, R. Iyengar. Wrote the paper: A. Ma'ayan, A. Mazloom, A. Malovannaya, R. Lanz, N. Clark.