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Research Article

Single Sample Expression-Anchored Mechanisms Predict Survival in Head and Neck Cancer

  • Xinan Yang,

    Affiliations: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Kelly Regan,

    Affiliation: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America

    Current address: Institute for Interventional Health Informatics, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Yong Huang,

    Affiliations: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Qingbei Zhang,

    Affiliations: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Jianrong Li,

    Affiliations: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America

    Current address: Institute for Interventional Health Informatics, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Tanguy Y. Seiwert,

    Affiliations: Section of Hematology/Oncology of the Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America, Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Ezra E. W. Cohen,

    Affiliations: Section of Hematology/Oncology of the Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America, Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America

    X
  • H. Rosie Xing,

    Affiliations: Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America, Departments of Pathology and of Cellular and Radiation Oncology, The University of Chicago, Chicago, Illinois, United States of America, Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois, United States of America

    X
  • Yves A. Lussier mail

    Lussier.y@gmail.com

    Affiliations: Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America, Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America, Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America, Departments of Pathology and of Cellular and Radiation Oncology, The University of Chicago, Chicago, Illinois, United States of America, Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois, United States of America, Computation Institute, Institute for Translational Medicine, and Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, United States of America

    Current address: Institute for Interventional Health Informatics, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Published: January 26, 2012
  • DOI: 10.1371/journal.pcbi.1002350

About the Authors

Xinan Yang, Kelly Regan, Yong Huang, Qingbei Zhang, Jianrong Li, Yves A. Lussier
Center for Biomedical Informatics, The University of Chicago, Chicago, Illinois, United States of America
Xinan Yang, Yong Huang, Qingbei Zhang, Jianrong Li, Yves A. Lussier
Section of Genetic Medicine, The University of Chicago, Chicago, Illinois, United States of America
Tanguy Y. Seiwert, Ezra E. W. Cohen
Section of Hematology/Oncology of the Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America
Tanguy Y. Seiwert, Ezra E. W. Cohen, H. Rosie Xing, Yves A. Lussier
Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois, United States of America
H. Rosie Xing, Yves A. Lussier
Departments of Pathology and of Cellular and Radiation Oncology, The University of Chicago, Chicago, Illinois, United States of America
H. Rosie Xing, Yves A. Lussier
Ludwig Center for Metastasis Research, The University of Chicago, Chicago, Illinois, United States of America
Yves A. Lussier
Computation Institute, Institute for Translational Medicine, and Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, United States of America

Corresponding Author

Email: Lussier.y@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XY YH YAL. Performed the experiments: XY QZ JL YAL. Analyzed the data: XY KR YH QZ JL TYS EEWC HRX YAL. Contributed reagents/materials/analysis tools: XY QZ JL YAL. Wrote the paper: XY KR YH QZ JL TYS EEWC HRX YAL. Overall supervision: YAL.