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Research Article

The Role of Conserved Waters in Conformational Transitions of Q61H K-ras

  • Priyanka Prakash,

    Affiliation: Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Abdallah Sayyed-Ahmad,

    Affiliation: Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

    Current address: Physics Department, Birzeit University, Birzeit, West Bank

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  • Alemayehu A. Gorfe mail

    Alemayehu.G.Abebe@uth.tmc.edu

    Affiliations: Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Center for Membrane Biology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Published: February 16, 2012
  • DOI: 10.1371/journal.pcbi.1002394

About the Authors

Priyanka Prakash, Abdallah Sayyed-Ahmad, Alemayehu A. Gorfe
Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America
Alemayehu A. Gorfe
Center for Membrane Biology, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Corresponding Author

Email: Alemayehu.G.Abebe@uth.tmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AAG. Performed the experiments: PP ASA AAG. Analyzed the data: PP ASA AAG. Contributed reagents/materials/analysis tools: PP ASA AAG. Wrote the paper: PP AAG.