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Research Article

Beyond the Binding Site: The Role of the β2 – β3 Loop and Extra-Domain Structures in PDZ Domains

  • Stefano Mostarda,

    Affiliation: Freiburg Institute for Advanced Studies, School of Soft Matter Research, Freiburg im Breisgau, Germany

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  • David Gfeller,

    Affiliation: Molecular Modeling, Swiss Institute of Bioinformatics, Lausanne, Switzerland

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  • Francesco Rao mail

    francesco.rao@frias.uni-freiburg.de

    Affiliation: Freiburg Institute for Advanced Studies, School of Soft Matter Research, Freiburg im Breisgau, Germany

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  • Published: March 08, 2012
  • DOI: 10.1371/journal.pcbi.1002429

About the Authors

Stefano Mostarda, Francesco Rao
Freiburg Institute for Advanced Studies, School of Soft Matter Research, Freiburg im Breisgau, Germany
David Gfeller
Molecular Modeling, Swiss Institute of Bioinformatics, Lausanne, Switzerland

Corresponding Author

Email: francesco.rao@frias.uni-freiburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SM FR. Performed the experiments: SM DG FR. Analyzed the data: SM DG FR. Contributed reagents/materials/analysis tools: SM DG FR. Wrote the paper: SM DG FR.