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Research Article

Adhesion Failures Determine the Pattern of Choroidal Neovascularization in the Eye: A Computer Simulation Study

  • Abbas Shirinifard mail,

    ashirini@indiana.edu

    Affiliation: The Biocomplexity Institute and Department of Physics, Indiana University Bloomington, Bloomington, Indiana, United States of America

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  • James Alexander Glazier,

    Affiliation: The Biocomplexity Institute and Department of Physics, Indiana University Bloomington, Bloomington, Indiana, United States of America

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  • Maciej Swat,

    Affiliation: The Biocomplexity Institute and Department of Physics, Indiana University Bloomington, Bloomington, Indiana, United States of America

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  • J. Scott Gens,

    Affiliation: The Biocomplexity Institute and Department of Physics, Indiana University Bloomington, Bloomington, Indiana, United States of America

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  • Fereydoon Family,

    Affiliation: Department of Physics, Emory University, Atlanta, Georgia, United States of America

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  • Yi Jiang,

    Affiliations: Department of Mathematics and Statistics, Georgia State University, Atlanta, Georgia, United States of America, Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Hans E. Grossniklaus

    Affiliation: L.F. Montgomery Ophthalmic Pathology Laboratory, Emory University, Atlanta, Georgia, United States of America

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  • Published: May 03, 2012
  • DOI: 10.1371/journal.pcbi.1002440

About the Authors

Abbas Shirinifard, James Alexander Glazier, Maciej Swat, J. Scott Gens
The Biocomplexity Institute and Department of Physics, Indiana University Bloomington, Bloomington, Indiana, United States of America
Fereydoon Family
Department of Physics, Emory University, Atlanta, Georgia, United States of America
Yi Jiang
Department of Mathematics and Statistics, Georgia State University, Atlanta, Georgia, United States of America
Yi Jiang
Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America
Hans E. Grossniklaus
L.F. Montgomery Ophthalmic Pathology Laboratory, Emory University, Atlanta, Georgia, United States of America

Corresponding Author

Email: ashirini@indiana.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AS JAG JSG FF YJ HEG. Performed the experiments: AS. Analyzed the data: AS JAG. Contributed reagents/materials/analysis tools: AS MS. Wrote the paper: AS JAG.