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Research Article

Parameters in Dynamic Models of Complex Traits are Containers of Missing Heritability

  • Yunpeng Wang,

    Affiliation: Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, Ås, Norway

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  • Arne B. Gjuvsland,

    Affiliation: Centre for Integrative Genetics, Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, Ås, Norway

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  • Jon Olav Vik,

    Affiliation: Centre for Integrative Genetics, Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, Ås, Norway

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  • Nicolas P. Smith,

    Affiliation: Department of Biomedical Engineering, St Thomas' Hospital, King's College London, London, United Kingdom

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  • Peter J. Hunter,

    Affiliation: Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand

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  • Stig W. Omholt mail

    stig.omholt@umb.no

    Affiliation: Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, Ås, Norway

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.pcbi.1002459

About the Authors

Yunpeng Wang, Stig W. Omholt
Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, Ås, Norway
Arne B. Gjuvsland, Jon Olav Vik
Centre for Integrative Genetics, Department of Mathematical Sciences and Technology, Norwegian University of Life Sciences, Ås, Norway
Nicolas P. Smith
Department of Biomedical Engineering, St Thomas' Hospital, King's College London, London, United Kingdom
Peter J. Hunter
Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand

Corresponding Author

Email: stig.omholt@umb.no

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YW ABG SWO. Analyzed the data: YW ABG. Wrote the paper: YW ABG JOV NPS PJH SWO. Established computational pipeline: YW ABG JOV. Contributed to computational pipeline: NPS PJH.