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Research Article

Fine-Tuning Tomato Agronomic Properties by Computational Genome Redesign

  • Javier Carrera mail,

    Javier.Carrera@synth-bio.org (JC); Agranell@ibmcp.upv.es (AG)

    Affiliations: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain, Synth-Bio Group, Institute of Systems and Synthetic Biology, Universite d'Evry Val d'Essonne - Genopole - CNRS UPS3201, Evry, France

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  • Asun Fernández del Carmen,

    Affiliation: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain

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  • Rafael Fernández-Muñoz,

    Affiliation: Instituto de Hortofruticultura Subtropical y Mediterranea “La Mayora” (IHSM-UMA-CSIC), Algarrobo-Costa, Malaga, Spain

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  • Jose Luis Rambla,

    Affiliation: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain

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  • Clara Pons,

    Affiliation: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain

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  • Alfonso Jaramillo,

    Affiliation: Synth-Bio Group, Institute of Systems and Synthetic Biology, Universite d'Evry Val d'Essonne - Genopole - CNRS UPS3201, Evry, France

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  • Santiago F. Elena,

    Affiliations: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain, The Santa Fe Institute, Santa Fe, New Mexico, United States of America

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  • Antonio Granell mail

    Javier.Carrera@synth-bio.org (JC); Agranell@ibmcp.upv.es (AG)

    Affiliation: Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain

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  • Published: June 07, 2012
  • DOI: 10.1371/journal.pcbi.1002528
  • Featured in PLOS Collections

About the Authors

Javier Carrera, Asun Fernández del Carmen, Jose Luis Rambla, Clara Pons, Santiago F. Elena, Antonio Granell
Instituto de Biologa Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas-UPV, Valencia, Spain
Javier Carrera, Alfonso Jaramillo
Synth-Bio Group, Institute of Systems and Synthetic Biology, Universite d'Evry Val d'Essonne - Genopole - CNRS UPS3201, Evry, France
Rafael Fernández-Muñoz
Instituto de Hortofruticultura Subtropical y Mediterranea “La Mayora” (IHSM-UMA-CSIC), Algarrobo-Costa, Malaga, Spain
Santiago F. Elena
The Santa Fe Institute, Santa Fe, New Mexico, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JC SFE AG. Performed the experiments: JC. Analyzed the data: JC AJ. Wrote the paper: JC SFE AG. Generated and phenotyped the RILs: RFM. Generated the volatile dataset: AFdC JLR. Generated the transcript dataset: CP.