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Research Article

Structure and Age Jointly Influence Rates of Protein Evolution

  • Macarena Toll-Riera,

    Affiliations: Evolutionary Genomics Group, Fundació Institut Municipal d'Investigació Mèdica (FIMIM)- Universitat Pompeu Fabra (UPF), Barcelona, Spain, Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • David Bostick,

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • M. Mar Albà mail,

    malba@imim.es (MMA); jplotkin@sas.upenn.edu (JBP)

    Affiliations: Evolutionary Genomics Group, Fundació Institut Municipal d'Investigació Mèdica (FIMIM)- Universitat Pompeu Fabra (UPF), Barcelona, Spain, Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain

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  • Joshua B. Plotkin mail

    malba@imim.es (MMA); jplotkin@sas.upenn.edu (JBP)

    Affiliation: Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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  • Published: May 31, 2012
  • DOI: 10.1371/journal.pcbi.1002542

About the Authors

Macarena Toll-Riera, M. Mar Albà
Evolutionary Genomics Group, Fundació Institut Municipal d'Investigació Mèdica (FIMIM)- Universitat Pompeu Fabra (UPF), Barcelona, Spain
Macarena Toll-Riera, David Bostick, Joshua B. Plotkin
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
M. Mar Albà
Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MTR DB MMA JBP. Performed the experiments: MTR DB. Analyzed the data: MTR DB MMA JBP. Wrote the paper: MTR DB MMA JBP.