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Research Article

Posterior Association Networks and Functional Modules Inferred from Rich Phenotypes of Gene Perturbations

  • Xin Wang,

    Affiliations: Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom, Department of Oncology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

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  • Mauro A. Castro,

    Affiliations: Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom, Department of Oncology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

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  • Klaas W. Mulder equal contributor,

    equal contributor Contributed equally to this work with: Klaas W. Mulder, Florian Markowetz

    Affiliation: Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom

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  • Florian Markowetz equal contributor mail

    equal contributor Contributed equally to this work with: Klaas W. Mulder, Florian Markowetz

    florian.markowetz@cancer.org.uk

    Affiliations: Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom, Department of Oncology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.pcbi.1002566

About the Authors

Xin Wang, Mauro A. Castro, Klaas W. Mulder, Florian Markowetz
Cancer Research UK Cambridge Research Institute, Cambridge, Cambridgeshire, United Kingdom
Xin Wang, Mauro A. Castro, Florian Markowetz
Department of Oncology, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom

Corresponding Author

Email: florian.markowetz@cancer.org.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KWM FM XW. Performed the experiments: XW KWM. Analyzed the data: XW MAC. Contributed reagents/materials/analysis tools: XW MAC. Wrote the paper: XW KWM FM.