Advertisement
Research Article

Deceleration of Fusion–Fission Cycles Improves Mitochondrial Quality Control during Aging

  • Marc Thilo Figge equal contributor,

    equal contributor Contributed equally to this work with: Marc Thilo Figge, Andreas S. Reichert

    Affiliations: Applied Systems Biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute and Friedrich Schiller University, Jena, Germany, Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany, Department of Systems Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany

    X
  • Andreas S. Reichert equal contributor,

    equal contributor Contributed equally to this work with: Marc Thilo Figge, Andreas S. Reichert

    Affiliations: Mitochondrial Biology, Medical School, Goethe University Frankfurt am Main, Frankfurt am Main, Germany, Mitochondrial Biology, Buchmann Institute for Molecular Life Sciences, Frankfurt am Main, Germany

    X
  • Michael Meyer-Hermann mail,

    michael.meyer-hermann@helmholtz-hzi.de(MMH); osiewacz@bio.uni-frankfurt.de (HDO)

    Affiliations: Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany, Department of Systems Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany

    X
  • Heinz D. Osiewacz mail

    michael.meyer-hermann@helmholtz-hzi.de(MMH); osiewacz@bio.uni-frankfurt.de (HDO)

    Affiliation: Faculty for Biosciences, Molecular Developmental Biology, Cluster of Excellence Macromolecular Complexes, Goethe University, Frankfurt am Main, Germany

    X
  • Published: June 28, 2012
  • DOI: 10.1371/journal.pcbi.1002576

About the Authors

Marc Thilo Figge
Applied Systems Biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute and Friedrich Schiller University, Jena, Germany
Marc Thilo Figge, Michael Meyer-Hermann
Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany
Marc Thilo Figge, Michael Meyer-Hermann
Department of Systems Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
Andreas S. Reichert
Mitochondrial Biology, Medical School, Goethe University Frankfurt am Main, Frankfurt am Main, Germany
Andreas S. Reichert
Mitochondrial Biology, Buchmann Institute for Molecular Life Sciences, Frankfurt am Main, Germany
Heinz D. Osiewacz
Faculty for Biosciences, Molecular Developmental Biology, Cluster of Excellence Macromolecular Complexes, Goethe University, Frankfurt am Main, Germany

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MTF ASR. Performed the experiments: MTF. Analyzed the data: MTF ASR MMH HDO. Contributed reagents/materials/analysis tools: MTF. Wrote the paper: MTF ASR HDO.