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Research Article

Network-Assisted Investigation of Combined Causal Signals from Genome-Wide Association Studies in Schizophrenia

  • Peilin Jia,

    Affiliations: Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Lily Wang,

    Affiliation: Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Ayman H. Fanous,

    Affiliations: Department of Psychiatry and Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America, Washington VA Medical Center, Washington, D.C., United States of America, Department of Psychiatry, Georgetown University School of Medicine, Washington, D.C., United States of America, Department of Psychiatry, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America

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  • Carlos N. Pato,

    Affiliation: Department of Psychiatry, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America

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  • Todd L. Edwards,

    Affiliations: Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Division of Epidemiolgy, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • The International Schizophrenia Consortium,

    For a list of members please see the Acknowledgments.

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  • Zhongming Zhao mail

    zhongming.zhao@vanderbilt.edu

    Affiliations: Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: July 05, 2012
  • DOI: 10.1371/journal.pcbi.1002587

About the Authors

Peilin Jia, Zhongming Zhao
Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Peilin Jia, Zhongming Zhao
Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Lily Wang
Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Ayman H. Fanous
Department of Psychiatry and Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America
Ayman H. Fanous
Washington VA Medical Center, Washington, D.C., United States of America
Ayman H. Fanous
Department of Psychiatry, Georgetown University School of Medicine, Washington, D.C., United States of America
Ayman H. Fanous, Carlos N. Pato
Department of Psychiatry, Keck School of Medicine of the University of Southern California, Los Angeles, California, United States of America
Todd L. Edwards
Center for Human Genetics Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Todd L. Edwards
Division of Epidemiolgy, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Zhongming Zhao
Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Corresponding Author

Email: zhongming.zhao@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PJ ZZ. Performed the experiments: PJ LW ZZ. Analyzed the data: PJ ZZ. Contributed reagents/materials/analysis tools: PJ AHF CNP. Wrote the paper: PJ LW AHF TLE ZZ.