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Research Article

Modeling Within-Host Dynamics of Influenza Virus Infection Including Immune Responses

  • Kasia A. Pawelek,

    Affiliation: Department of Mathematics and Statistics, Oakland University, Rochester, Michigan, United States of America

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  • Giao T. Huynh,

    Affiliation: Department of Mathematics and Statistics, Oakland University, Rochester, Michigan, United States of America

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  • Michelle Quinlivan,

    Affiliation: Virology Unit, Irish Equine Centre, Johnstown, Naas, Co. Kildare, Ireland

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  • Ann Cullinane,

    Affiliation: Virology Unit, Irish Equine Centre, Johnstown, Naas, Co. Kildare, Ireland

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  • Libin Rong mail,

    rong2@oakland.edu (LR); asp@lanl.gov (ASP)

    Affiliation: Department of Mathematics and Statistics, Oakland University, Rochester, Michigan, United States of America

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  • Alan S. Perelson mail

    rong2@oakland.edu (LR); asp@lanl.gov (ASP)

    Affiliation: Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

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  • Published: June 28, 2012
  • DOI: 10.1371/journal.pcbi.1002588

About the Authors

Kasia A. Pawelek, Giao T. Huynh, Libin Rong
Department of Mathematics and Statistics, Oakland University, Rochester, Michigan, United States of America
Michelle Quinlivan, Ann Cullinane
Virology Unit, Irish Equine Centre, Johnstown, Naas, Co. Kildare, Ireland
Alan S. Perelson
Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LR. Performed the experiments: KAP LR ASP. Analyzed the data: KAP LR. Contributed reagents/materials/analysis tools: GTH MQ AC ASP. Wrote the paper: KAP LR ASP.