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Research Article

Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data

  • Haipeng Xing equal contributor mail,

    equal contributor Contributed equally to this work with: Haipeng Xing, Yifan Mo, Will Liao

    xing@ams.sunysb.edu

    Affiliation: Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America

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  • Yifan Mo equal contributor,

    equal contributor Contributed equally to this work with: Haipeng Xing, Yifan Mo, Will Liao

    Affiliations: Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America, Computational Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

    X
  • Will Liao equal contributor,

    equal contributor Contributed equally to this work with: Haipeng Xing, Yifan Mo, Will Liao

    Affiliations: Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America, Computational Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America

    X
  • Michael Q. Zhang

    Affiliations: Computational Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America, Bioinformatics Division, Tsinghua University, Beijing, China

    Current address: Department of Molecular and Cell Biology, The University of Texas at Dallas, Richardson, Texas, United States of America.

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  • Published: July 26, 2012
  • DOI: 10.1371/journal.pcbi.1002613

About the Authors

Haipeng Xing, Yifan Mo, Will Liao
Applied Mathematics and Statistics, Stony Brook University, Stony Brook, New York, United States of America
Yifan Mo, Will Liao, Michael Q. Zhang
Computational Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
Michael Q. Zhang
Bioinformatics Division, Tsinghua University, Beijing, China

Corresponding Author

Email: xing@ams.sunysb.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HX YM WL MQZ. Analyzed the data: HX YM WL. Contributed reagents/materials/analysis tools: HX MQZ. Wrote the paper: HX YM WL.