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Research Article

Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation

  • Laurent F. Thomas,

    Affiliations: Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, Interagon AS, Laboratoriesenteret, Trondheim, Norway

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  • Pål Sætrom mail

    pal.satrom@ntnu.no

    Affiliations: Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, Interagon AS, Laboratoriesenteret, Trondheim, Norway, Department of Computer and Information Science, Norwegian University of Science and Technology, Trondheim, Norway

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  • Published: August 16, 2012
  • DOI: 10.1371/journal.pcbi.1002621

About the Authors

Laurent F. Thomas, Pål Sætrom
Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway
Laurent F. Thomas, Pål Sætrom
Interagon AS, Laboratoriesenteret, Trondheim, Norway
Pål Sætrom
Department of Computer and Information Science, Norwegian University of Science and Technology, Trondheim, Norway

Corresponding Author

Email: pal.satrom@ntnu.no

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LFT PS. Performed the experiments: LFT. Analyzed the data: LFT PS. Contributed reagents/materials/analysis tools: LFT. Wrote the paper: LFT PS.