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Research Article

High Resolution Genome Wide Binding Event Finding and Motif Discovery Reveals Transcription Factor Spatial Binding Constraints

  • Yuchun Guo,

    Affiliations: Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Shaun Mahony mail,

    mahony@mit.edu (SM); gifford@mit.edu (DKG)

    Affiliation: Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • David K. Gifford mail

    mahony@mit.edu (SM); gifford@mit.edu (DKG)

    Affiliation: Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

    X
  • Published: August 09, 2012
  • DOI: 10.1371/journal.pcbi.1002638

About the Authors

Yuchun Guo
Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
Yuchun Guo, Shaun Mahony, David K. Gifford
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YG SM DKG. Performed the experiments: YG. Analyzed the data: YG SM DKG. Contributed reagents/materials/analysis tools: YG. Wrote the paper: YG SM DKG.