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Research Article

What Evidence Is There for the Homology of Protein-Protein Interactions?

  • Anna C. F. Lewis,

    Affiliations: Department of Statistics, University of Oxford, Oxford, United Kingdom, Systems Biology Doctoral Training Centre, University of Oxford, Oxford, United Kingdom

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  • Nick S. Jones,

    Affiliations: Department of Mathematics, Imperial College, London, United Kingdom, Department of Physics, University of Oxford, Oxford, United Kingdom, CABDyN Complexity Centre, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom

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  • Mason A. Porter,

    Affiliations: CABDyN Complexity Centre, University of Oxford, Oxford, United Kingdom, Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom

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  • Charlotte M. Deane mail

    deane@stats.ox.ac.uk

    Affiliations: Department of Statistics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.pcbi.1002645

About the Authors

Anna C. F. Lewis, Charlotte M. Deane
Department of Statistics, University of Oxford, Oxford, United Kingdom
Anna C. F. Lewis
Systems Biology Doctoral Training Centre, University of Oxford, Oxford, United Kingdom
Nick S. Jones
Department of Mathematics, Imperial College, London, United Kingdom
Nick S. Jones
Department of Physics, University of Oxford, Oxford, United Kingdom
Nick S. Jones, Mason A. Porter
CABDyN Complexity Centre, University of Oxford, Oxford, United Kingdom
Nick S. Jones, Charlotte M. Deane
Oxford Centre for Integrative Systems Biology, University of Oxford, Oxford, United Kingdom
Mason A. Porter
Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom

Corresponding Author

Email: deane@stats.ox.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ACFL NSJ MAP CMD. Performed the experiments: ACFL. Analyzed the data: ACFL. Wrote the paper: ACFL NSJ MAP CMD.