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Research Article

Mutual Repression Enhances the Steepness and Precision of Gene Expression Boundaries

  • Thomas R. Sokolowski,

    Affiliation: FOM Institute AMOLF, Amsterdam, The Netherlands

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  • Thorsten Erdmann,

    Affiliation: University of Heidelberg, Institute for Theoretical Physics, Heidelberg, Germany

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  • Pieter Rein ten Wolde mail

    tenwolde@amolf.nl

    Affiliation: FOM Institute AMOLF, Amsterdam, The Netherlands

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  • Published: August 30, 2012
  • DOI: 10.1371/journal.pcbi.1002654

About the Authors

Thomas R. Sokolowski, Pieter Rein ten Wolde
FOM Institute AMOLF, Amsterdam, The Netherlands
Thorsten Erdmann
University of Heidelberg, Institute for Theoretical Physics, Heidelberg, Germany

Corresponding Author

Email: tenwolde@amolf.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TRS TE PRtW. Performed the experiments: TRS. Analyzed the data: TRS. Contributed reagents/materials/analysis tools: TRS TE. Wrote the paper: TRS TE PRtW. Designed the software used for simulations and analysis: TRS TE.