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Research Article

High-throughput Computer Method for 3D Neuronal Structure Reconstruction from the Image Stack of the Drosophila Brain and Its Applications

  • Ping-Chang Lee,

    Affiliation: Department of Computer Science, National Chiao Tung University, HsinChu, Taiwan

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  • Chao-Chun Chuang,

    Affiliations: Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, Taiwan, National Center for High-Performance Computing, HsinChu, Taiwan

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  • Ann-Shyn Chiang,

    Affiliations: Institute of Biotechnology, National Tsing Hua University, HsinChu, Taiwan, Brain Research Center, National Tsing Hua University, HsinChu, Taiwan

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  • Yu-Tai Ching mail

    ytc@cs.nctu.edu.tw

    Affiliation: Department of Computer Science, National Chiao Tung University, HsinChu, Taiwan

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.pcbi.1002658

About the Authors

Ping-Chang Lee, Yu-Tai Ching
Department of Computer Science, National Chiao Tung University, HsinChu, Taiwan
Chao-Chun Chuang
Institute of Bioinformatics and Systems Biology, National Chiao Tung University, HsinChu, Taiwan
Chao-Chun Chuang
National Center for High-Performance Computing, HsinChu, Taiwan
Ann-Shyn Chiang
Institute of Biotechnology, National Tsing Hua University, HsinChu, Taiwan
Ann-Shyn Chiang
Brain Research Center, National Tsing Hua University, HsinChu, Taiwan

Corresponding Author

Email: ytc@cs.nctu.edu.tw

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PCL YTC. Performed the experiments: PCL CCC. Analyzed the data: PCL CCC. Contributed reagents/materials/analysis tools: ASC. Wrote the paper: PCL YTC.