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Research Article

Evolutionary Dynamics on Protein Bi-stability Landscapes can Potentially Resolve Adaptive Conflicts

  • Tobias Sikosek mail,

    sikosek@wwu.de

    Affiliation: Evolutionary Bioinformatics Group, Institute for Evolution and Biodiversity, University of Münster, Münster, Germany

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  • Erich Bornberg-Bauer,

    Affiliation: Evolutionary Bioinformatics Group, Institute for Evolution and Biodiversity, University of Münster, Münster, Germany

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  • Hue Sun Chan

    Affiliation: Departments of Biochemistry, Molecular Genetics, and Physics, University of Toronto, Toronto, Ontario, Canada

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.pcbi.1002659

About the Authors

Tobias Sikosek, Erich Bornberg-Bauer
Evolutionary Bioinformatics Group, Institute for Evolution and Biodiversity, University of Münster, Münster, Germany
Hue Sun Chan
Departments of Biochemistry, Molecular Genetics, and Physics, University of Toronto, Toronto, Ontario, Canada

Corresponding Author

Email: sikosek@wwu.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TS EBB HSC. Performed the experiments: TS. Analyzed the data: TS. Wrote the paper: TS EBB HSC.