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Research Article

Stress-Induced Impairment of a Working Memory Task: Role of Spiking Rate and Spiking History Predicted Discharge

  • David M. Devilbiss mail,

    ddevilbiss@wisc.edu

    Affiliation: University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Rick L. Jenison,

    Affiliation: University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Craig W. Berridge

    Affiliation: University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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  • Published: September 13, 2012
  • DOI: 10.1371/journal.pcbi.1002681
  • Featured in PLOS Collections

About the Authors

David M. Devilbiss, Rick L. Jenison, Craig W. Berridge
University of Wisconsin-Madison, Madison, Wisconsin, United States of America

Corresponding Author

Email: ddevilbiss@wisc.edu

Competing Interests

I have read the journal's policy and have the following potential conflicts: RLJ reports no conflict of interest. DMD is the founder of NexStep Biomarkers, LLC. NexStep Biomarkers had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. NexStep Biomarkers, does not employ anyone who worked on this project, hold patents related to this project, sell products related to this project, or provided consultation on this project. This manuscript provides no financial gain for NexStep Biomarkers. Dr. Berridge has received expert witness fees from Teva Pharmaceutical, Activis, Aurobindo Pharmaceuticals, Mylan Pharmaceuticals, and Apotex.

Author Contributions

Conceived and designed the experiments: DMD CWB. Performed the experiments: DMD. Analyzed the data: DMD. Contributed reagents/materials/analysis tools: DMD RLJ. Wrote the paper: DMD CWB. Designed the analysis and wrote the Matlab code: DMD RLJ.