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Research Article

Spike-Timing Dependence of Structural Plasticity Explains Cooperative Synapse Formation in the Neocortex

  • Moritz Deger mail,

    deger@bcf.uni-freiburg.de

    Affiliation: Bernstein Center Freiburg, Albert-Ludwig University, Freiburg, Germany

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  • Moritz Helias,

    Affiliation: Computational and Systems Neuroscience, Institute of Neuroscience and Medicine (INM-6), Research Center Jülich, Jülich, Germany

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  • Stefan Rotter,

    Affiliations: Bernstein Center Freiburg, Albert-Ludwig University, Freiburg, Germany, Faculty of Biology, Albert-Ludwig University, Freiburg, Germany

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  • Markus Diesmann

    Affiliations: Bernstein Center Freiburg, Albert-Ludwig University, Freiburg, Germany, Computational and Systems Neuroscience, Institute of Neuroscience and Medicine (INM-6), Research Center Jülich, Jülich, Germany, Medical Faculty, RWTH Aachen University, Aachen, Germany

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  • Published: September 20, 2012
  • DOI: 10.1371/journal.pcbi.1002689

About the Authors

Moritz Deger, Stefan Rotter, Markus Diesmann
Bernstein Center Freiburg, Albert-Ludwig University, Freiburg, Germany
Moritz Helias, Markus Diesmann
Computational and Systems Neuroscience, Institute of Neuroscience and Medicine (INM-6), Research Center Jülich, Jülich, Germany
Stefan Rotter
Faculty of Biology, Albert-Ludwig University, Freiburg, Germany
Markus Diesmann
Medical Faculty, RWTH Aachen University, Aachen, Germany

Corresponding Author

Email: deger@bcf.uni-freiburg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M. Deger, M. Helias, S. Rotter, M. Diesmann. Performed the experiments: M. Deger, M. Helias, S. Rotter, M. Diesmann. Analyzed the data: M. Deger, M. Helias, S. Rotter, M. Diesmann. Contributed reagents/materials/analysis tools: M. Deger, M. Helias. Wrote the paper: M. Deger, M. Helias, S. Rotter, M. Diesmann.