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Research Article

Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations

  • Noah S. Bieler,

    Affiliation: Laboratory for Physical Chemistry, ETH Zürich, Zurich, Switzerland

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  • Tuomas P. J. Knowles,

    Affiliation: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

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  • Daan Frenkel,

    Affiliation: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

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  • Robert Vácha mail

    robertvacha@gmail.com

    Affiliations: Department of Chemistry, University of Cambridge, Cambridge, United Kingdom, National Centre for Biomolecular Research, Faculty of Science and CEITEC - Central European Institute of Technology, Masaryk University, Brno-Bohunice, Czech Republic

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  • Published: October 11, 2012
  • DOI: 10.1371/journal.pcbi.1002692

About the Authors

Noah S. Bieler
Laboratory for Physical Chemistry, ETH Zürich, Zurich, Switzerland
Tuomas P. J. Knowles, Daan Frenkel, Robert Vácha
Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
Robert Vácha
National Centre for Biomolecular Research, Faculty of Science and CEITEC - Central European Institute of Technology, Masaryk University, Brno-Bohunice, Czech Republic

Corresponding Author

Email: robertvacha@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TPJK DF RV. Performed the experiments: NSB. Analyzed the data: NSB RV. Wrote the paper: NSB TPJK DF RV.