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Research Article

3D Reconstruction and Standardization of the Rat Vibrissal Cortex for Precise Registration of Single Neuron Morphology

  • Robert Egger,

    Affiliation: Digital Neuroanatomy, Max Planck Florida Institute, Jupiter, Florida, United States of America

    Current address: Computational Neuroanatomy Group, Max Planck Institute for Biological Cybernetics, Tübingen, Germany

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  • Rajeevan T. Narayanan,

    Affiliation: Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, the Netherlands

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  • Moritz Helmstaedter,

    Affiliation: Structure of Neocortical Circuits Group, Max Planck Institute of Neurobiology, Martinsried, Germany

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  • Christiaan P. J. de Kock,

    Affiliation: Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, the Netherlands

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  • Marcel Oberlaender mail

    marcel.oberlaender@tuebingen.mpg.de

    Affiliation: Digital Neuroanatomy, Max Planck Florida Institute, Jupiter, Florida, United States of America

    Current address: Computational Neuroanatomy Group, Max Planck Institute for Biological Cybernetics, Tübingen, Germany

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  • Published: December 20, 2012
  • DOI: 10.1371/journal.pcbi.1002837

About the Authors

Robert Egger, Marcel Oberlaender
Digital Neuroanatomy, Max Planck Florida Institute, Jupiter, Florida, United States of America
Rajeevan T. Narayanan, Christiaan P. J. de Kock
Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, Amsterdam, the Netherlands
Moritz Helmstaedter
Structure of Neocortical Circuits Group, Max Planck Institute of Neurobiology, Martinsried, Germany

Corresponding Author

Email: marcel.oberlaender@tuebingen.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MO. Performed the experiments: RTN CPJdK. Analyzed the data: RE MO. Contributed reagents/materials/analysis tools: RE. Wrote the paper: MO. Conceived and developed an earlier version of the registration tool: MH. Developed and implemented the present image processing and registration tools: RE.