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Research Article

Phosphorylation Variation during the Cell Cycle Scales with Structural Propensities of Proteins

  • Stefka Tyanova,

    Affiliations: Genome-Oriented Bioinformatics Department, Technische Universität München, Freising, Germany, Department for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany

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  • Jürgen Cox,

    Affiliation: Department for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany

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  • Jesper Olsen,

    Affiliation: Department of Proteomics, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

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  • Matthias Mann,

    Affiliations: Department for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany, Department of Proteomics, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

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  • Dmitrij Frishman mail

    d.frishman@wzw.tum.de

    Affiliations: Genome-Oriented Bioinformatics Department, Technische Universität München, Freising, Germany, Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Institute of Bioinformatics and Systems Biology, Neuherberg, Germany

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  • Published: January 10, 2013
  • DOI: 10.1371/journal.pcbi.1002842

About the Authors

Stefka Tyanova, Dmitrij Frishman
Genome-Oriented Bioinformatics Department, Technische Universität München, Freising, Germany
Stefka Tyanova, Jürgen Cox, Matthias Mann
Department for Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany
Jesper Olsen, Matthias Mann
Department of Proteomics, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark
Dmitrij Frishman
Helmholtz Center Munich - German Research Center for Environmental Health (GmbH), Institute of Bioinformatics and Systems Biology, Neuherberg, Germany

Corresponding Author

Email: d.frishman@wzw.tum.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Supervised the work: JC DF. Conceived and designed the experiments: ST JC DF. Performed the experiments: JO. Analyzed the data: ST. Wrote the paper: ST JC MM DF.