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Research Article

Divide and Conquer: Functional Segregation of Synaptic Inputs by Astrocytic Microdomains Could Alleviate Paroxysmal Activity Following Brain Trauma

  • Vladislav Volman mail,

    volman@salk.edu

    Affiliations: Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America, Center for Theoretical Biological Physics, University of California at San Diego, La Jolla, California, United States of America, L-3 Applied Technologies/Simulation, Engineering, & Testing, San Diego, California, United States of America

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  • Maxim Bazhenov,

    Affiliation: Department of Cell Biology and Neuroscience, University of California at Riverside, La Jolla, California, United States of America

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  • Terrence J. Sejnowski

    Affiliations: Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America, Center for Theoretical Biological Physics, University of California at San Diego, La Jolla, California, United States of America, Division of Biological Sciences, University of California at San Diego, La Jolla, California, United States of America

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  • Published: January 24, 2013
  • DOI: 10.1371/journal.pcbi.1002856

About the Authors

Vladislav Volman, Terrence J. Sejnowski
Howard Hughes Medical Institute, Computational Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California, United States of America
Vladislav Volman, Terrence J. Sejnowski
Center for Theoretical Biological Physics, University of California at San Diego, La Jolla, California, United States of America
Vladislav Volman
L-3 Applied Technologies/Simulation, Engineering, & Testing, San Diego, California, United States of America
Maxim Bazhenov
Department of Cell Biology and Neuroscience, University of California at Riverside, La Jolla, California, United States of America
Terrence J. Sejnowski
Division of Biological Sciences, University of California at San Diego, La Jolla, California, United States of America

Corresponding Author

Email: volman@salk.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VV MB TJS. Performed the experiments: VV. Analyzed the data: VV MB TJS. Contributed reagents/materials/analysis tools: VV MB TJS. Wrote the paper: VV MB TJS.