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Research Article

The Underlying Molecular and Network Level Mechanisms in the Evolution of Robustness in Gene Regulatory Networks

  • Mario Pujato equal contributor,

    equal contributor Contributed equally to this work with: Mario Pujato, Thomas MacCarthy

    Affiliations: Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Thomas MacCarthy equal contributor,

    equal contributor Contributed equally to this work with: Mario Pujato, Thomas MacCarthy

    Affiliations: Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Applied Mathematics and Statistics, SUNY, Stony Brook, New York, United States of America

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  • Andras Fiser mail,

    andras.fiser@einstein.yu.edu (AF); aviv.bergman@einstein.yu.edu (AB)

    Affiliations: Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America, Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Aviv Bergman mail

    andras.fiser@einstein.yu.edu (AF); aviv.bergman@einstein.yu.edu (AB)

    Affiliation: Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America

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  • Published: January 03, 2013
  • DOI: 10.1371/journal.pcbi.1002865

About the Authors

Mario Pujato, Thomas MacCarthy, Andras Fiser, Aviv Bergman
Department of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America
Mario Pujato, Andras Fiser
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York, United States of America
Thomas MacCarthy
Department of Applied Mathematics and Statistics, SUNY, Stony Brook, New York, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AF AB. Performed the experiments: MP TM. Analyzed the data: MP TM. Wrote the paper: MP TM.