Advertisement
Research Article

Significance Analysis of Prognostic Signatures

  • Andrew H. Beck mail,

    abeck2@bidmc.harvard.edu (AHB); bhaibeka@ircm.qc.ca (BHK)

    Affiliation: Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Nicholas W. Knoblauch,

    Affiliation: Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Marco M. Hefti,

    Affiliation: Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Jennifer Kaplan,

    Affiliation: Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Stuart J. Schnitt,

    Affiliation: Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America

    X
  • Aedin C. Culhane,

    Affiliations: Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • Markus S. Schroeder,

    Affiliations: Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • Thomas Risch,

    Affiliations: Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America

    X
  • John Quackenbush,

    Affiliations: Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America, Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

    X
  • Benjamin Haibe-Kains mail

    abeck2@bidmc.harvard.edu (AHB); bhaibeka@ircm.qc.ca (BHK)

    Affiliation: Bioinformatics and Computational Genomics Laboratory, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Quebec, Canada

    X
  • Published: January 24, 2013
  • DOI: 10.1371/journal.pcbi.1002875

About the Authors

Andrew H. Beck, Nicholas W. Knoblauch, Marco M. Hefti, Jennifer Kaplan, Stuart J. Schnitt
Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America
Aedin C. Culhane, Markus S. Schroeder, Thomas Risch, John Quackenbush
Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
Aedin C. Culhane, Markus S. Schroeder, Thomas Risch, John Quackenbush
Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America
John Quackenbush
Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
Benjamin Haibe-Kains
Bioinformatics and Computational Genomics Laboratory, Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Quebec, Canada

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AHB BHK. Performed the experiments: AHB BHK. Analyzed the data: AHB BHK. Contributed reagents/materials/analysis tools: AHB NWK MMH JK SJS ACC MSS TR BHK. Wrote the paper: AHB JQ BHK.