About the Authors

W. Lee Pang

Current address: Genomatica, Inc., San Diego, California, United States of America.

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Amardeep Kaur

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Alexander V. Ratushny

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Aleksandar Cvetkovic

Current address: Pall Life Sciences, Boston, Massachusetts, United States of America.

Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America

Sunil Kumar

Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America

Min Pan

Affiliation Institute for Systems Biology, Seattle, Washington, United States of America

Adam P. Arkin

Affiliation Department of Bioengineering, University of California, Berkeley, California, United States of America

John D. Aitchison

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Seattle Biomedical Research Institute, Seattle, Washington, United States of America

Michael W. W. Adams

Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America

Nitin S. Baliga

Nitin.Baliga@systemsbiology.org

Affiliations Institute for Systems Biology, Seattle, Washington, United States of America, Department of Microbiology, University of Washington, Seattle, Washington, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WLP NSB. Performed the experiments: WLP AK AC SK MP. Analyzed the data: WLP AVR APA JDA NSB. Contributed reagents/materials/analysis tools: AC SK MWWA. Wrote the paper: WLP NSB.