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Research Article

Positional Bias of MHC Class I Restricted T-Cell Epitopes in Viral Antigens Is Likely due to a Bias in Conservation

  • Yohan Kim,

    Affiliation: La Jolla Institute for Allergy & Immunology, La Jolla, California, United States of America

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  • Jonathan W. Yewdell,

    Affiliation: Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America

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  • Alessandro Sette,

    Affiliation: La Jolla Institute for Allergy & Immunology, La Jolla, California, United States of America

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  • Bjoern Peters mail

    bpeters@liai.org

    Affiliation: La Jolla Institute for Allergy & Immunology, La Jolla, California, United States of America

    X
  • Published: January 24, 2013
  • DOI: 10.1371/journal.pcbi.1002884

About the Authors

Yohan Kim, Alessandro Sette, Bjoern Peters
La Jolla Institute for Allergy & Immunology, La Jolla, California, United States of America
Jonathan W. Yewdell
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America

Corresponding Author

Email: bpeters@liai.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YK JWY BP. Performed the experiments: YK. Analyzed the data: YK JWY AS BP. Wrote the paper: YK JWY AS BP.