About the Authors

Gary R. Mirams

gary.mirams@cs.ox.ac.uk

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Christopher J. Arthurs

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Miguel O. Bernabeu

Affiliations CoMPLEX, Maths & Physical Sciences, University College London, London, United Kingdom, Centre for Computational Science, University College London, London, United Kingdom

Rafel Bordas

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Jonathan Cooper

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Alberto Corrias

Affiliation Department of Bioengineering, National University of Singapore, Singapore, Singapore

Yohan Davit

Affiliation Oxford Centre for Collaborative Applied Mathematics, Mathematical Institute, University of Oxford, Oxford, United Kingdom

Sara-Jane Dunn

Affiliation Computational Science Laboratory, Microsoft Research, Cambridge, United Kingdom

Alexander G. Fletcher

Affiliation Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom

Daniel G. Harvey

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Megan E. Marsh

Affiliation Department of Mathematics and Statistics, University of Saskatchewan, Saskatoon, Canada

James M. Osborne

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Pras Pathmanathan

Affiliations Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom, Food and Drug Administration, Silver Spring, Maryland, United States of America

Joe Pitt-Francis

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

James Southern

Affiliation Fujitsu Laboratories of Europe, Hayes Park, London, United Kingdom

Nejib Zemzemi

Affiliation CARMEN project, INRIA Bordeaux Sud-Ouest, Talence, France

David J. Gavaghan

Affiliation Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom

Competing Interests

I have read the journal's policy and have the following conflicts: GRM and DJG have received research support from GlaxoSmithKline Plc.

Author Contributions

Designed and wrote the software: GRM CJA MOB RB JC AC YD SJD AGF DGH MEM JMO PP JPF JS NZ DJG. Conceived and designed the experiments: GRM YD AGF JMO DGH PP JPF. Performed the experiments: GRM AGF DGH JMO PP. Analyzed the data: GRM RB AGF JMO PP. Wrote the paper: GRM MOB RB JC YD SJD AGF PP JPF DJG.