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Research Article

Generative FDG-PET and MRI Model of Aging and Disease Progression in Alzheimer's Disease

  • Juergen Dukart mail,

    dukart@cbs.mpg.de

    Affiliations: LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland, Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

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  • Ferath Kherif,

    Affiliation: LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland

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  • Karsten Mueller,

    Affiliation: Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

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  • Stanislaw Adaszewski,

    Affiliation: LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland

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  • Matthias L. Schroeter,

    Affiliations: Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, Day Clinic of Cognitive Neurology, University of Leipzig, Leipzig, Germany, LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany, Consortium for Frontotemporal Lobar Degeneration, Leipzig, Germany

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  • Richard S. J. Frackowiak,

    Affiliation: LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland

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  • Bogdan Draganski,

    Affiliations: LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland, Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

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  • for the Alzheimer's Disease Neuroimaging Initiative

    Please see the acknowledgments for further details of the Alzheimer's Disease Neuroimaging Initiative.

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  • Published: April 04, 2013
  • DOI: 10.1371/journal.pcbi.1002987
  • Featured in PLOS Collections

About the Authors

Juergen Dukart, Ferath Kherif, Stanislaw Adaszewski, Richard S. J. Frackowiak, Bogdan Draganski
LREN, Département des Neurosciences Cliniques, CHUV, Université de Lausanne, Lausanne, Switzerland
Juergen Dukart, Karsten Mueller, Matthias L. Schroeter, Bogdan Draganski
Max-Planck-Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
Matthias L. Schroeter
Day Clinic of Cognitive Neurology, University of Leipzig, Leipzig, Germany
Matthias L. Schroeter
LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany
Matthias L. Schroeter
Consortium for Frontotemporal Lobar Degeneration, Leipzig, Germany

Corresponding Author

Email: dukart@cbs.mpg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JD MLS RSJF BD. Performed the experiments: JD. Analyzed the data: JD. Contributed reagents/materials/analysis tools: JD FK KM SA. Wrote the paper: JD FK KM SA MLS RSJF BD.