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Research Article

Lifespan Differences in Hematopoietic Stem Cells are Due to Imperfect Repair and Unstable Mean-Reversion

  • Hans B Sieburg mail,

    hsieburg@sanfordburnham.org

    Affiliation: Stem Cell and Regenerative Medicine Program, The Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Giulio Cattarossi,

    Affiliation: Stem Cell and Regenerative Medicine Program, The Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Christa E. Muller-Sieburg

    Affiliation: Stem Cell and Regenerative Medicine Program, The Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Published: April 18, 2013
  • DOI: 10.1371/journal.pcbi.1003006

About the Authors

Hans B Sieburg, Giulio Cattarossi, Christa E. Muller-Sieburg
Stem Cell and Regenerative Medicine Program, The Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

Corresponding Author

Email: hsieburg@sanfordburnham.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CEMS. Performed the experiments: GC. Analyzed the data: HBS. Wrote the paper: HBS CEMS.