About the Authors

Yuguo Yu

Affiliations Centre for Computational Systems Biology, School of Life Sciences, Fudan University, Shanghai, People's Republic of China, Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

Thomas S. McTavish

Affiliation Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

Michael L. Hines

Affiliation Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

Gordon M. Shepherd

Affiliation Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

Cesare Valenti

Affiliation Department of Mathematics and Informatics, University of Palermo, Palermo, Italy

Michele Migliore

michele.migliore@cnr.it

Affiliations Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Institute of Biophysics, National Research Council, Palermo, Italy

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YY MLH GMS MM. Performed the experiments: YY MM. Analyzed the data: YY TSM MLH GMS CV MM. Contributed reagents/materials/analysis tools: MLH CV. Wrote the paper: YY TSM GMS MM.