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Research Article

Colocalization of Coregulated Genes: A Steered Molecular Dynamics Study of Human Chromosome 19

  • Marco Di Stefano,

    Affiliation: International School for Advanced Studies (SISSA), Trieste, Italy

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  • Angelo Rosa mail,

    anrosa@sissa.it (AR); michelet@sissa.it (CM)

    Affiliation: International School for Advanced Studies (SISSA), Trieste, Italy

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  • Vincenzo Belcastro,

    Affiliation: Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland

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  • Diego di Bernardo,

    Affiliations: Telethon Institute of Genetics and Medicine (TIGEM), Napoli, Italy, Department of Informatics and Systems Engineering, University “Federico II”, Napoli, Italy

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  • Cristian Micheletti mail

    anrosa@sissa.it (AR); michelet@sissa.it (CM)

    Affiliation: International School for Advanced Studies (SISSA), Trieste, Italy

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  • Published: March 28, 2013
  • DOI: 10.1371/journal.pcbi.1003019

About the Authors

Marco Di Stefano, Angelo Rosa, Cristian Micheletti
International School for Advanced Studies (SISSA), Trieste, Italy
Vincenzo Belcastro
Philip Morris International R&D, Philip Morris Products S.A., Neuchâtel, Switzerland
Diego di Bernardo
Telethon Institute of Genetics and Medicine (TIGEM), Napoli, Italy
Diego di Bernardo
Department of Informatics and Systems Engineering, University “Federico II”, Napoli, Italy

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MDS AR VB DdB CM. Performed the experiments: MDS. Analyzed the data: MDS AR CM. Contributed reagents/materials/analysis tools: MDS AR VB DdB CM. Wrote the paper: MDS AR CM.