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Research Article

Network Signatures of Survival in Glioblastoma Multiforme

  • Vishal N. Patel mail,

    vishal.patel2@case.edu

    Affiliation: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Giridharan Gokulrangan,

    Affiliation: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Salim A. Chowdhury,

    Affiliation: School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

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  • Yanwen Chen,

    Affiliation: Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Andrew E. Sloan,

    Affiliation: Brain Tumor & Neuro-Oncology Center, University Hospital-Case Medical Center, Cleveland, Ohio, United States of America

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  • Mehmet Koyutürk,

    Affiliations: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Jill Barnholtz-Sloan,

    Affiliations: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Mark R. Chance

    Affiliations: Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America

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  • Published: September 19, 2013
  • DOI: 10.1371/journal.pcbi.1003237

About the Authors

Vishal N. Patel, Giridharan Gokulrangan, Mehmet Koyutürk, Jill Barnholtz-Sloan, Mark R. Chance
Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, United States of America
Salim A. Chowdhury
School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
Yanwen Chen, Jill Barnholtz-Sloan, Mark R. Chance
Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
Andrew E. Sloan
Brain Tumor & Neuro-Oncology Center, University Hospital-Case Medical Center, Cleveland, Ohio, United States of America
Mehmet Koyutürk
Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, Ohio, United States of America

Corresponding Author

Email: vishal.patel2@case.edu

Competing Interests

MRC, SAC, and MK have competing interests in the software CRANE.

Author Contributions

Conceived and designed the experiments: VNP GG MK MRC. Performed the experiments: VNP GG SAC. Analyzed the data: VNP GG SAC YC. Contributed reagents/materials/analysis tools: AES JBS MRC. Wrote the paper: VNP MK MRC.