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Research Article

An Allosteric Signaling Pathway of Human 3-Phosphoglycerate Kinase from Force Distribution Analysis

  • Zoltan Palmai,

    Affiliation: Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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  • Christian Seifert,

    Affiliation: Molecular Biomechanics, Heidelberger Institut für Theoretische Studien gGmbH, Heidelberg, Germany

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  • Frauke Gräter mail,

    frauke.graeter@h-its.org (FG); balog.erika@med.semmelweis-univ.hu (EB)

    Affiliations: Molecular Biomechanics, Heidelberger Institut für Theoretische Studien gGmbH, Heidelberg, Germany, MPG-CAS Partner Institute and Key Laboratory for Computational Biology, Shanghai, China

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  • Erika Balog mail

    frauke.graeter@h-its.org (FG); balog.erika@med.semmelweis-univ.hu (EB)

    Affiliation: Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary

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  • Published: January 23, 2014
  • DOI: 10.1371/journal.pcbi.1003444

About the Authors

Zoltan Palmai, Erika Balog
Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, Hungary
Christian Seifert, Frauke Gräter
Molecular Biomechanics, Heidelberger Institut für Theoretische Studien gGmbH, Heidelberg, Germany
Frauke Gräter
MPG-CAS Partner Institute and Key Laboratory for Computational Biology, Shanghai, China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZP CS FG EB. Performed the experiments: ZP CS. Analyzed the data: ZP CS FG EB. Contributed reagents/materials/analysis tools: ZP CS. Wrote the paper: ZP CS FG EB.